Advanced nCycle Peptide Designer (Senior/Principal)
Lead innovative peptide design and synthesis, driving innovation in drug discovery of oral macrocycles
Backed by leading life sciences investors such as Novo Holdings and Forbion, Orbis is empowered to invest in groundbreaking technologies like the field-leading oral macrocycle design and development platform, nGen. Orbis Medicines operates at the intersection of science and technology, integrating cutting-edge tools like artificial intelligence (AI) and machine learning (ML) to accelerate the drug discovery process.
With established facilities and highly skilled professionals in Lausanne, Switzerland, Orbis Medicines is establishing discovery capabilities at a new Copenhagen site. The site is expected to house a team of 15 experienced professionals, bringing the total workforce to 30, including the Lausanne site.
As Advanced nCycle Peptide Designer at Orbis Medicines, you will join the newly established team in Copenhagen, Denmark, and contribute to discovering and developing innovative therapeutic solutions.
With direct report to the VP, Drug Discovery, you will be a vital member of the growing discovery team and drive the progression of design and synthesis of nCycles projects. You’ll play a pivotal role in establishing workflows and fostering cross-functional collaborations. This position offers significant personal development opportunities by taking on exciting projects as the pipeline evolves.
Your main tasks include:
- Defining the strategy for designing orally available nCycles in close cross-functional collaboration.
- Being a MedChem lead and/or discovery project lead.
- Leading design and synthesis of nCycles towards development candidate selection.
Your qualifications include over 10 years of industry experience in peptide chemistry, with expertise in designing peptides and/or macrocycles, ideally for oral use. You possess in-depth knowledge of the drug discovery process, particularly in the context of peptide-based therapeutics.
You have a PhD in chemistry/pharmaceutical science or a related field.
You are a person with strong scientific communication skills, effectively articulating strategies and expectations. You thrive in leading and motivating cross-functional teams, fostering collaboration and ensuring accountability for project outcomes. With a keen ability to anticipate challenges, you develop contingency plans and adapt quickly to new methodologies and technologies, applying critical and creative thinking to devise innovative solutions.
Orbis Medicines offers a unique opening to join a growing start-up and opportunities to grow in an innovative, collaborative, and passionate environment that will pioneer a new era for oral macrocycle drug discovery.
Travelling: Limited.
Domicile: Orbis Medicines’ facility in Copenhagen.
At Unique Human Capital, we are committed to promoting diversity and including all perspectives. Thus, we encourage all qualified candidates to apply for the position. All applications must be in English and are treated confidentially.
Orbis Medicines is a biotechnology company focused on pioneering a new oral macrocycle drug discovery era. Macrocycles are a large and diverse family of compounds with highly desirable therapeutic properties. The Orbis nGen platform is designed to systematically explore the macrocycle chemical space using a highly automated chemistry platform and deliver oral macrocycle drug candidates – nCycles – suitable for intra- and extracellular targets. Orbis’ programs are focused on high-value oral alternatives to blockbuster biologic drugs and targets challenging for established modalities. Orbis Medicines was founded by Novo Holdings.
Read more at http://www.orbismedicines.com.
Do you have any questions about the position?
Then feel free to contact the following people directly. All applications must be in English and are treated confidentially.
